Infections following gender-affirming vaginoplasty

Reviewed by Cindy Noyes

Bottom line:  As gender-affirming surgeries are becoming more prevalent, efforts to identify epidemiology and trends must be reported to reduce risk of post operative infectious complications.

Sheth and colleagues describe their single center experience with the commonest infectious complications following gender affirming vaginoplasty. The most common vaginoplasties performed were penile inversions (332) followed by robotic assisted (64) vs sigmoid vaginoplasties (2), and almost all were primary surgeries.  Urinary tract infections were the most common infections (17%, n=70), followed by SSI (5.5%, n-=22). E coli most common uropathogen (38%) followed by kleb PNA (8.5%). SSIs were often treated empirically and cultures not collected. 

Reference: Sheth R, et al.  infections following gender-affirming vaginoplasty: a single center experience.  OFID.  2024.  https://doi.org/10.1093./ofid.ofae526.

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