Reviewed by Sara Karaba, MD, PhD, MHS, Johns Hopkins University Patients with central lines are at risk for infection, including when outside the hospital. Surveillance…

Reviewed by Cindy Noyes, MD, University of Vermont Medical Center, Burlington, VT When pathogenic organisms are recovered, positive central line cultures may predict subsequent bacteremia…

Reviewed by Barry Rittmann, MD, MPH, Virginia Commonwealth University A recent article in the American Journal of Infection Control evaluated interventions to reverse CLABSI trends…

Jen Cihlar, DO, Vanderbilt University Medical Center In vitro and in animal model studies demonstrate synergistic bactericidal activity of amoxicillin and cefdinir without rise in…

Reviewed by Jose Lucar, MD, The George Washington University In a cohort of previously healthy cryptococcal meningitis survivors, persistently positive follow up antigen titers were…

Reviewed by: David Cluck, PharmD; East Tennessee State University How to reconcile the findings of this study when juxtaposed with the findings of the BLING-3…

Extended-infusion β-lactam Therapy – “It’s Not for Everyone” Clinical value of follow-up antigen titers in cryptococcal meningitis among immunocompetent survivors Can you teach an old…

Reviewed by Jose Lucar, MD, The George Washington University Bottom line: A network meta-analysis concludes that TMP-SMX remains the most effective agent for PJP prophylaxis…

Reviewed by Sara Karaba, MD, PhD, MHS, Johns Hopkins University Bottom line: A new study indicates that narrowing antibiotic coverage decreases the risk of subsequent…

Reviewed by Jen Cihlar, DO, Vanderbilt University Medical Center Bottom line: In a hypothesis-generating study,5-7 days versus 10 days for treatment of C diff with…