This document describes useful and practical metrics and surveillance considerations for measuring MDROs and the infections they cause in the practice of infection prevention and control in healthcare settings. These metrics are designed to aid healthcare workers in documenting trends over time within their facility and should not be used for interfacility comparison.The following MDROs are addressed: (1) methicillin‐resistant Staphylococcus aureus; (2) vancomycin‐resistant Enterococcus species; (3) multidrug‐resistant gram‐negative bacilli; and (4) vancomycin‐resistant S. aureus. We convened a working group of experts that reviewed current practices, the peer‐reviewed literature, and existing guidelines on surveillance strategies and key metrics.

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